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Article

Lissencephaly-1 mutations enhance traumatic brain injury outcomes in Drosophila.

Genetics - 2 Mar 2023

Katzenberger Rebeccah J, Ganetzky Barry, Wassarman David A

Abstract excerpt

Traumatic brain injury (TBI) outcomes vary greatly among individuals, but most of the variation remains unexplained. Using a Drosophila melanogaster TBI model and 178 genetically diverse lines from the Drosophila Genetic Reference Panel (DGRP), we investigated the role that genetic variation plays in determining TBI outcomes. Following injury at 20-27 days old, DGRP lines varied considerably in mortality within...

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Identifiers

PMID: 36683334
DOI: 10.1093/genetics/iyad008
PMCID: PMC9991514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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