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Article

Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models

6 Feb 2018

Abstract excerpt

Traumatic brain injury (TBI) has been predicted to be a predisposing factor for amyotrophic lateral sclerosis (ALS) and other neurological disorders. Despite the importance of TBI in ALS progression, the underlying cellular and molecular mechanisms are still an enigma. Here, we examined the contribution of TBI as an extrinsic factor and investigated whether TBI influences the susceptibility of developing...

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PMID: 29432563
DOI: 10.1093/hmg/ddy047

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