Article
In Vitro and In Vivo Phenotypes of Venezuelan, Eastern and Western Equine Encephalitis Viruses Derived from cDNA Clones of Human Isolates.
Viruses - 20 Dec 2022
Gardner Christina L, Sun Chengqun, Dunn Matthew D, Gilliland Theron C, Trobaugh Derek W, Terada Yutaka, Reed Douglas S, Hartman Amy L, Klimstra William B
Abstract excerpt
The Department of Defense recently began an effort to improve and standardize virus challenge materials and efficacy determination strategies for testing therapeutics and vaccines. This includes stabilization of virus genome sequences in cDNA form where appropriate, use of human-derived virus isolates, and noninvasive strategies for determination of challenge virus replication. Eventually, it is desired that...
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