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RGS2 promotes estradiol biosynthesis by trophoblasts during human pregnancy

18 Jan 2023

Abstract excerpt

Production of estradiol (E2) by the placenta during human pregnancy ensures successful maintenance of placental development and fetal growth by stimulating trophoblast proliferation and the differentiation of cytotrophoblasts into syncytiotrophoblasts. Decreased levels of E2 are closely associated with obstetrical diseases such as preeclampsia (PE) in the clinic. However, the mechanisms underlying the inhibition...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36653442
DOI: 10.1038/s12276-023-00927-z

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