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Article

JAZF1 safeguards human endometrial stromal cells survival and decidualization by repressing the transcription of G0S2

27 May 2023

Abstract excerpt

Decidualization of human endometrial stromal cells (hESCs) is essential for the maintenance of pregnancy, which depends on the fine-tuned regulation of hESCs survival, and its perturbation contributes to pregnancy loss. However, the underlying mechanisms responsible for functional deficits in decidua from recurrent spontaneous abortion (RSA) patients have not been elucidated. Here, we observed that JAZF1 was...

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PMID: 37244968
DOI: 10.1038/s42003-023-04931-x

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