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Article

Formyl peptide receptor-2 is decreased in foetal growth restriction and contributes to placental dysfunction

18 Dec 2017

Abstract excerpt

STUDY QUESTION: What is the association between placental formyl peptide receptor 2 (FPR2) and trophoblast and endothelial functions in pregnancies affected by foetal growth restriction (FGR)? SUMMARY ANSWER: Reduced FPR2 placental expression in idiopathic FGR results in significantly altered trophoblast differentiation and endothelial function in vitro. WHAT IS KNOWN ALREADY: FGR is associated with placental...

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PMID: 29272530
DOI: 10.1093/molehr/gax067

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