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Article

Replication of association at the LPP and UBASH3A loci in a UK autoimmune Addison's disease cohort.

European journal of endocrinology - 10 Jan 2023

Howarth Sophie, Sneddon Georgina, Allinson Kathleen R, Razvi Salman, Mitchell Anna L, Pearce Simon H S

Abstract excerpt

Autoimmune Addison's disease (AAD) arises from a complex interplay between multiple genetic susceptibility polymorphisms and environmental factors. The first genome wide association study (GWAS) with patients from Scandinavian Addison's registries has identified association signals at four novel loci in the genes LPP, SH2B3, SIGLEC5, and UBASH3A. To verify these novel risk loci, we performed a case-control...

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Identifiers

PMID: 36651163
DOI: 10.1093/ejendo/lvac010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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