Article
Heritability of Addison's disease and prevalence of associated autoimmunity in a cohort of 112,100 Swedish twins.
Endocrine - 1 Dec 2017
Skov Jakob, Höijer Jonas, Magnusson Patrik K E, Ludvigsson Jonas F, Kämpe Olle, Bensing Sophie
Abstract excerpt
PURPOSE: The pathophysiology behind autoimmune Addison's disease (AAD) is poorly understood, and the relative influence of genetic and environmental factors remains unclear. In this study, we examined the heritability of AAD and explored disease-associated autoimmune comorbidity among Swedish twins. METHODS: A population-based longitudinal cohort of 112,100 Swedish twins was used to calculate the heritability of...
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