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Nanoscopic Assessment of Anti-SARS-CoV-2 Spike Neutralizing Antibody Using High-Speed AFM

15 Jan 2023

Abstract excerpt

Anti-spike neutralizing antibodies (S NAbs) have been developed for prevention and treatment against COVID-19. The nanoscopic characterization of the dynamic interaction between spike proteins and S NAbs remains difficult. By using high-speed atomic force microscopy (HS-AFM), we elucidate the molecular property of an S NAb and its interaction with spike proteins. The S NAb appeared as monomers with a Y...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36641798
DOI: 10.1021/acs.nanolett.2c04270

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