Article
High real-world effectiveness of 12-week elbasvir/grazoprevir without resistance testing in the treatment of patients with HCV genotype 1a infection in Norway.
Scandinavian journal of gastroenterology - 1 Mar 2023
Leiva Rafael A, Bergersen Bente M, Finbråten Ane-Kristine, Sandvei Per Kristian, Simonsen Øystein, Rosseland Carola M, Hagen Karin, Young Lital, Roberts R Scott, Mikkelsen Yngve, Singh Ravinder, Lagging Martin, Dalgard Olav
Abstract excerpt
BACKGROUND AND AIMS: The recommended treatment duration of hepatitis C virus (HCV) genotype 1a (GT1a) infection with elbasvir/grazoprevir (EBR/GZR) in the presence of a high baseline viral load and resistance associated substitutions (RAS) is 16 weeks with ribavirin added. The objective of this study was to evaluate the real-world effectiveness of 12 weeks of EBR/GZR without ribavirin and regardless of baseline...
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