Article
Clinical outcome of Brazilian patients with non-small cell lung cancer in early stage harboring rare mutations in epidermal growth factor receptor.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 2023
Machado-Rugolo J, Baldavira C M, Prieto T G, Olivieri E H R, Fabro A T, Rainho C A, Castelli E C, Ribolla P E M, Ab'Saber A M, Takagaki T, Nagai M A, Capelozzi V L
Abstract excerpt
The common epidermal growth factor receptor (EGFR) mutations, such as the L858R point mutation in exon 21 and the in-frame deletional mutation in exon 19, have been definitively associated with response to EGFR-tyrosine kinase inhibitors (EGFR-TKI). However, the clinical outcome and response to treatment for many other rarer mutations are still unclear. In this study, we report the results of Brazilian patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.