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Development and clinical applications of an enclosed automated targeted NGS library preparation system.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2023

Shi Chao, Feng Yan, Sun Rui, Chen Jun, Zhao Yanhong, Wang Zhizhong, Xie Shifei, Zhou Jiantao, Yang Lingjian, Cao Xinkai, Feng Junnan, Zhang Cuiyun, Wei Bing, Wang Xiaoyan, Chang Yuxi, Zhao Jiuzhou, Wang Zhaosong, Zheng Jiawen, Liu Jiaxiuyu, Chantratita Wasun, Xiong Lei, Zhang Dadong, Chen Caifu, Ma Jie

Abstract excerpt

The rapid development of next-generation sequencing (NGS) technology has promoted its wide clinical application in precision medicine for oncology. However, laborious and time-consuming manual operations, highly skilled personnel requirements, and cross-contamination are major challenges for the clinical implementation of NGS technology-based tests. The Automated NGS Diagnostic Solutions (ANDiS) 500 system is a...

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PMID: 36627008
DOI: 10.1016/j.cca.2023.117224

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