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Article

Rapid and Flexible RT-qPCR Surveillance Platforms To Detect SARS-CoV-2 Mutations.

Microbiology spectrum - 14 Feb 2023

Spiess Katja, Gunalan Vithiagaran, Marving Ellinor, Nielsen Sofie Holdflod, Jørgensen Michelle G P, Fomsgaard Anna S, Nielsen Line, Alfaro-Núñez Alonzo, Karst Søren M, Mortensen Shila, Rasmussen Morten, Lassaunière Ria, Rosenstierne Maiken Worsøe, Polacek Charlotta, Fonager Jannik, Cohen Arieh S, Nielsen Claus, Fomsgaard Anders

Abstract excerpt

Multiple mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) increase transmission, disease severity, and immune evasion and facilitate zoonotic or anthropozoonotic infections. Four such mutations, ΔH69/V70, L452R, E484K, and N501Y, occurred in the SARS-CoV-2 spike glycoprotein in combinations that allow the simultaneous detection of VOCs. Here, we present two...

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Identifiers

PMID: 36625603
DOI: 10.1128/spectrum.03591-22
PMCID: PMC9927487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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