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Article

Pan-cancer molecular analysis of EGFR large fragment deletion in the Asian population.

Cancer medicine - 1 Apr 2023

Pu Jun, Guo Huannan, Yu Ruoying, Ou Qiuxiang, Bao Hua, Wu Xue, Tang Sanyuan, Chang Qingyong

Abstract excerpt

BACKGROUND: Large fragment deletion (LFD) of EGFR was associated with carcinogenesis in many types of cancers. However, the molecular features of EGFR-LFD have not been studied in the Asian cancer population. METHOD: Here we retrospectively analyzed the targeted sequencing data from a large cancer database. RESULTS: EGFR-LFD was detected at a frequency of 0.03% with EGFRvIII being the most frequently observed...

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Identifiers

PMID: 36622089
DOI: 10.1002/cam4.5603
PMCID: PMC10134361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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