Article
Impact of m6A demethylase (ALKBH5, FTO) genetic polymorphism and expression levels on the development of pulmonary tuberculosis.
Frontiers in cellular and infection microbiology - 1 Jan 2022
Zhang Tian-Ping, Li Rui, Wang Li-Jun, Li Hong-Miao
Abstract excerpt
Objective: The m6A methylation was involved in the pathogenesis of pulmonary tuberculosis (PTB), and our study aimed to reveal the potential association of m6A demethylase (ALKBH5, FTO) genes variation, expression levels and PTB. Methods: Eight SNPs (ALKBH5 gene rs8400, rs9913266, rs12936694, rs4925144 and FTO gene rs6499640, , , ) were selected for genotyping by SNPscan technique in...
