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Association of HSD17B13 and PNPLA3 With Liver Enzymes and Fibrosis in Hispanic/Latino Individuals of Diverse Genetic Ancestries.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Sept 2023

Rutledge Stephanie M, Soper Emily R, Ma Ning, Pejaver Vikas, Friedman Scott L, Branch Andrea D, Kenny Eimear E, Belbin Gillian M, Abul-Husn Noura S

Abstract excerpt

BACKGROUND & AIMS: Genetic variants affecting liver disease risk vary among racial and ethnic groups. Hispanics/Latinos in the United States have a high prevalence of PNPLA3 I148M, which increases liver disease risk, and a low prevalence of HSD17B13 predicted loss-of-function (pLoF) variants, which reduce risk. Less is known about the prevalence of liver disease-associated variants among Hispanic/Latino...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 36610497
DOI: 10.1016/j.cgh.2022.12.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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