Article
Identification of vacuolar autophagic aggregates in the skeletal muscles of inbred C57BL/6NCrl mice.
Laboratory animals - 1 Jun 2023
De Biase Davide, Pagano Teresa Bruna, Malanga Donatella, Russo Valeria, Piegari Giuseppe, d'Aquino Ilaria, Iovane Valentina, Scarfò Marzia, Papparella Serenella, Wojcik Slawomir, Paciello Orlando
Abstract excerpt
A comprehensive pathological analysis of inbred strains is essential to define strain-specific spontaneous lesions and to understand whether a specific phenotype results from experimental intervention or reflects a naturally occurring disease. This study aimed to report and describe a novel condition affecting the skeletal muscles of an inbred C57BL/6NCrl mouse colony characterised by large sarcoplasmic vacuoles...
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