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The obesity-autophagy-cancer axis: Mechanistic insights and therapeutic perspectives

1 Feb 2024

Abstract excerpt

Autophagy, a self-degradative process vital for cellular homeostasis, plays a significant role in adipose tissue metabolism and tumorigenesis. This review aims to elucidate the complex interplay between autophagy, obesity, and cancer development, with a specific emphasis on how obesity-driven changes affect the regulation of autophagy and subsequent implications for cancer risk. The burgeoning epidemic of obesity...

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Share to Adipose Tissue and Metabolism
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PMID: 38309540
DOI: 10.1016/j.semcancer.2024.01.003

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