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Article

SIGIRR-caspase-8 signaling mediates endothelial apoptosis in Kawasaki disease

4 Jan 2023

Abstract excerpt

BACKGROUND: Kawasaki disease (KD) is a kind of vasculitis with unidentified etiology. Given that the current diagnosis and therapeutic strategy of KD are mainly dependent on clinical experiences, further research to explore its pathological mechanisms is warranted. METHODS: Enzyme linked immunosorbent assay (ELISA) was used to measure the serum levels of SIGIRR, TLR4 and caspase-8. Western blotting was applied to...

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PMID: 36600293
DOI: 10.1186/s13052-022-01401-8

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