Article
Brain-derived neurotrophic factor G196A (rs6265) gene polymorphism increases Turner syndrome susceptibility.
Biotechnology & genetic engineering reviews - 1 Oct 2023
Farooqui Anam, Anwer Ayesha, Alam Aftab, Bagabir Sali Abubaker, Haque Shafiul, Khadgawat Rajesh, Kazim Syed Naqi, Ali Sher, Ishrat Romana
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family. It plays a significant role in the regulation of brain metabolic activity, modification of synaptic efficacy, and enhances neuronal survival. A common naturally occurring allelic variation, i.e. G196A (Val66 Met, rs6265) of the BDNF gene is implicated in neuroplasticity. This study analyzes its expression levels and determines...
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