Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RUNX2 stabilization by long non-coding RNAs contributes to hypertrophic changes in human chondrocytes

23 Nov 2022

Abstract excerpt

Background: Chondrocyte hypertrophy has been implicated in endochondral ossification and osteoarthritis (OA). In OA, hypertrophic chondrocytes contribute to the destruction and focal calcification of the joint cartilage. Although studies in this field have remarkably developed the modulation of joint inflammation using gene therapy and regeneration of damaged articular cartilage using cell therapy, studies that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Osteoarthritis Treatment and Mechanisms
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36594090
DOI: 10.7150/ijbs.74895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RUNX2 stabilization by long non-coding RNAs contributes to hypertrophic changes in human chondrocytesPMID 36594090Read ↗

Transcription Factors in Cartilage Homeostasis and OsteoarthritisSemantic proximity Read ↗

The emerging role of lncRNAs in chondrocytes from osteoarthritis patientsSemantic proximity Read ↗

MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritisSemantic proximity Read ↗

Phenotypic instability of chondrocytes in osteoarthritis: on a path to hypertrophy.Semantic proximity Read ↗

Long Intergenic Noncoding RNAs Mediate the Human Chondrocyte Inflammatory Response and Are Differentially Expressed in Osteoarthritis CartilageSemantic proximity Read ↗

Runx3 alleviates osteoarthritis through microRNA regulating multiple inflammation-related pathwaysSemantic proximity Read ↗

Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytesSemantic proximity Read ↗

Elucidating Epigenetic Regulation by Identifying Functional cis‐Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular CartilageSemantic proximity Read ↗

LncRNA HOXC-AS3 Prevents Chondrocyte Senescence and Osteoarthritis Progression Through miR-615-3p Sponging and RRBP1 InteractionSemantic proximity Read ↗

Runx1 protects against the pathological progression of osteoarthritisSemantic proximity Read ↗

Long non-coding RNA DANCR regulates proliferation and apoptosis of chondrocytes in osteoarthritis via miR-216a-5p-JAK2-STAT3 axisSemantic proximity Read ↗

Involvement of long non-coding RNAs in the pathogenesis of rheumatoid arthritisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.