Article

LncRNA HOXC-AS3 Prevents Chondrocyte Senescence and Osteoarthritis Progression Through miR-615-3p Sponging and RRBP1 Interaction

2025-06-18

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Osteoarthritis (OA) is a prevalent chronic joint disease characterized by progressive cartilage degeneration, significantly impairing quality of life for millions worldwide. Cellular senescence has emerged as a pivotal driver of OA pathogenesis, with senescent chondrocytes exhibiting a senescence-associated secretory phenotype that exacerbates tissue degradat...

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Literature Corpus work: 14be2856-e2c7-52a7-848c-d91b233ef65b
DOI: 10.21203/rs.3.rs-6379719/v1

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