Article
Hybrid Metabolic Activity-Related Prognostic Model and Its Effect on Tumor in Renal Cell Carcinoma.
Journal of healthcare engineering - 1 Jan 2022
Yu Lei, Ding Lei, Wang Zhong-Yuan, Zhao Xing-Zhi, Wang Yu-Hao, Liang Chao, Li Jie
Abstract excerpt
Background: Tumor cells with a hybrid metabolic state, in which glycolysis and oxidative phosphorylation (OXPHOS) can be used, usually have a strong ability to adapt to different stress environments due to their metabolic plasticity. However, few studies on tumor cells with this phenotype have been conducted in the field of renal cell carcinoma (RCC). Methods: The metabolic pathway (glycolysis, OXPHOS) related...
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