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Single-cell RNA sequencing reveals regulation of fetal ovary development in the monkey (Macaca fascicularis)

28 Dec 2020

Abstract excerpt

Germ cells are vital for reproduction and heredity. However, the mechanisms underlying female germ cell development in primates, especially in late embryonic stages, remain elusive. Here, we performed single-cell RNA sequencing of 12,471 cells from whole fetal ovaries, and explored the communications between germ cells and niche cells. We depicted the two waves of oogenesis at single-cell resolution and...

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PMID: 33372178
DOI: 10.1038/s41421-020-00219-0

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