Article
Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.
British journal of cancer - 1 Mar 2023
Cifuentes Guadalupe A, Santiago Adrián, Méndez Blanco Lucía, Fueyo María, López Martínez Esther, Soria Raquel, Martín López Irene, Cucarella Beltrán Pepa, Pardo-Coto Pablo, Rodriguez-Rubi David, Urquilla Karla, Durán Noelia S, Álvarez Rebeca, Lago Claudia G, Otero Andrea, Diñeiro Marta, Capín Raquel, Cadiñanos Juan, Cabanillas Rubén
Abstract excerpt
BACKGROUND: Liquid biopsy and Integrative Genomic Profiling (IGP) are yet to be implemented into routine Radiation Oncology. Here we assess the utility of germline, tumour and circulating cell-free DNA-based genomic analyses for the clinical management of early-stage and oligometastatic cancer patients treated by precision radiotherapy. METHODS: We performed germline, tissue- and liquid biopsy NGS panels on 50...
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