Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Handling of Germline Findings in Clinical Comprehensive Cancer Genomic Profiling.

Acta medica Okayama - 1 Dec 2022

Okazawa-Sakai Mika, Yamamoto Yasuko, Futagawa Mashu, Okamura Miki, Miyawaki Satoko, Nishina Tomohiro, Takehara Kazuhiro, Kozuki Toshiyuki, Tomida Shuta, Hyodo Ichinosuke, Ohsumi Shozo, Hirasawa Akira

Abstract excerpt

Patients found to have presumed germline pathogenic variants (PGPVs) during comprehensive genomic profiling (CGP) require genetic counseling (GC) referrals. We retrospectively investigated the outcomes of patients with PGPVs. Among 159 patients who underwent CGP, we recommended GC for the 16 patients with PGPVs (3 with [FG group] and 13 without [G Group] a family/personal history of hereditary cancer) as well as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Neoplasms

Source

Identifiers

PMID: 36549769
DOI: 10.18926/AMO/64117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Handling of Germline Findings in Clinical Comprehensive Cancer Genomic Profiling.PMID 36549769Read ↗

When Should Tumor Genomic Profiling Prompt Consideration of Germline Testing?Semantic proximity Read ↗

[Hereditary Tumor Medical Care in the Age of Cancer Genomic Medicine].Semantic proximity Read ↗

Germline reflex BRCA1/2 testing following tumor-only comprehensive genomic profiling: why, when, and how.Semantic proximity Read ↗

Germline pathogenic variants identification through Comprehensive Cancer Genome ProfilingSemantic proximity Read ↗

Germline sequencing for presumed germline pathogenic variants via tumor-only comprehensive genomic profilingSemantic proximity Read ↗

BRCA1/2 Variants Identified Through Tumor Genomic Profiling: Assessing Genetic Counseling Outcomes.Semantic proximity Read ↗

Discrepancies between tumor genomic profiling and germline genetic testing.Semantic proximity Read ↗

Genetic Counseling and Germline Testing in the Era of Tumor Sequencing: A Cohort StudySemantic proximity Read ↗

Hereditary cancer testing challenges: assembling the analytical pieces to solve the patient clinical puzzle.Semantic proximity Read ↗

A germline and somatic mutation sorting (GeMSort) algorithm for extracting presumed germline pathogenic variants in liquid genomic profiling: Insights from Database of Center for Cancer Genomics and Advanced Therapeutics (C-CAT)Semantic proximity Read ↗

Germline evaluation of patients undergoing tumor genomic profiling: An academic cancer center's experience with implementing a germline review protocol.Semantic proximity Read ↗

Germline Pathogenic Variants Identified in Patients With Genitourinary Malignancies Undergoing Universal Testing: A Multisite Single-Institution Prospective Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.