Article
Generation of neutralizing and non-neutralizing monoclonal antibodies against H7N9 influenza virus.
Emerging microbes & infections - 1 Jan 2020
Yang Fan, Xiao Yixin, Lu Rufeng, Chen Bin, Liu Fumin, Wang Liyan, Yao Hangping, Wu Nanping, Wu Haibo
Abstract excerpt
The H7N9 viruses have been circulating for six years. The insertion of a polybasic cleavage site in the haemagglutinin (HA) protein of H7N9 has resulted in the emergence of a highly pathogenic (HP) avian influenza virus. Currently, there are limited studies on neutralizing monoclonal antibodies(mAbs) against HP H7N9 AIVs. In this study, mice were immunized with inactivated H7N9 vaccine of A/ZJU01/PR8/2013 to...
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