Article
Association between FLT3-ITD and additional chromosomal abnormalities in the prognosis of acute promyelocytic leukemia.
The Journal of international medical research - 1 Dec 2022
Vu Minh Phuong, Nguyen Cuc Nhung, Vu Hoang, Nguyen Tuyet Mai, Nguyen Tuan Tung, Pham Phuong Thao
Abstract excerpt
OBJECTIVES: Internal tandem duplications of the Fms-like tyrosine kinase 3 gene (FLT3-ITD) and additional chromosomal abnormalities (ACA) are prognostic factors in patients with acute promyelocytic leukemia (APL). This study aimed to determine the effect of the association between FLT3-ITD and ACA in the prognosis of APL. METHODS: This was a retrospective cohort study including 60 patients with APL treated with...
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