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Genetically predicted selenium concentrations and thyroid function: A two-sample Mendelian randomization study.

Clinical endocrinology - 1 Jun 2023

Huang Hui-Jun, Wang Shan-Shan, Jin Ming-Min, Cheng Bin-Wei, Liu Yu, Liu Xiao-Chen, Yu Qiu-Yan, Yang Xin-Jun

Abstract excerpt

OBJECTIVE: The impact of selenium (Se) on human thyroid function remains unclear, with inconsistent results from recent epidemiological studies. Moreover, the observed associations are prone to bias due to potential confounding and reverse causation. Mendelian randomization (MR) analysis facilitates the large minimization of biases produced by environmental and lifestyle influences, providing unconfounded...

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PMID: 36536522
DOI: 10.1111/cen.14867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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