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Article

Molecular Characterization of Multifocal Granular Cell Tumors.

The American journal of surgical pathology - 1 Mar 2023

Dehner Carina A, Schroeder Molly C, Lyu Yang, Bell Robert, Borcherding Dana C, Moon Tyler, Hirbe Angela, Chrisinger John S A

Abstract excerpt

Granular cell tumors (GrCT) were recently found to be driven by inactivating mutations in vacuolar H + -ATPase (V-ATPase) genes, most frequently ATP6AP1 and ATP6AP2 . Multifocal presentation is present in ~10% of cases; however, the relationship between multifocal tumors in a given patient has not been elucidated. We hypothesized that benign-appearing multifocal GrCT are molecularly distinct whereas paired...

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PMID: 36534754
DOI: 10.1097/PAS.0000000000001992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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