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Article

Penetrance of Gastric Adenocarcinoma Susceptibility Genes: A Systematic Review.

Annals of surgical oncology - 1 Mar 2023

Hosseini Sahar, Acar Ahmet, Sen Meghdeep, Meeder Kiersten, Singh Preeti, Yin Kanhua, Sutton Jeffrey M, Hughes Kevin

Abstract excerpt

BACKGROUND: Gastric adenocarcinoma (GAC) is the fifth most common cancer in the world, and the presence of germline pathogenic variants has been linked with approximately 5% of gastric cancer diagnoses. Multiple GAC susceptibility genes have been identified, but information regarding the risk associated with pathogenic variants in these genes remains obscure. We conducted a systematic review of existing studies...

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Identifiers

PMID: 36528743
DOI: 10.1245/s10434-022-12829-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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