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Disease spectrum of gastric cancer susceptibility genes.

Medical oncology (Northwood, London, England) - 24 Mar 2021

McKinley Sophia K, Singh Preeti, Yin Kanhua, Wang Jin, Zhou Jingan, Bao Yujia, Wu Menghua, Pathak Kush, Mullen John T, Braun Danielle, Hughes Kevin S

Abstract excerpt

Pathogenic variants in germline cancer susceptibility genes can increase the risk of a large number of diseases. Our study aims to assess the disease spectrum of gastric cancer susceptibility genes and to develop a comprehensive resource of gene-disease associations for clinicians. Twenty-seven potential germline gastric cancer susceptibility genes were identified from three review articles and from six commonly...

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PMID: 33760988
DOI: 10.1007/s12032-021-01495-w

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