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Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)

2019-10-17

Abstract excerpt

<h4>ABSTRACT</h4> We conducted the largest study of snoring using data from the UK Biobank ( n ∼ 408,000; snorers ∼152,000). A genome-wide association study (GWAS) identified 42 genome-wide significant loci, with a SNP-based heritability estimate of ∼10% on the liability scale. Genetic correlations with body mass index, alcohol intake, smoking, schizophrenia, anorexia nervosa and neuroticism were observed. Gene-...

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Literature Corpus work
af5d44cf-622c-5040-ba96-477f410f20e0
DOI
10.1101/808691
Open publication

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Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank (n=408,317)DOI 10.1101/808691
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