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Article

Mendelian randomization analyses identified bioavailable testosterone mediates the effect of sex hormone-binding globulin on prostate cancer.

Andrology - 1 Sept 2023

Wan Bangbei, Lu Likui, Lv Cai

Abstract excerpt

OBJECTIVE: A better knowledge of the hormonal etiology of prostate cancer is essential for its prevention and treatment. The goal of this study was to provide causal estimates of the connection between sex hormone-binding globulin and prostate cancer and investigate the possible mediating function of other modifiable risk indicators. METHODS: We used two-step, two-sample multivariable Mendelian randomization...

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Identifiers

PMID: 36524281
DOI: 10.1111/andr.13358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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