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Article

A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome.

Journal of the American Heart Association - 20 Dec 2022

Singh Gautam K, McClenaghan Conor, Aggarwal Manish, Gu Hongjie, Remedi Maria S, Grange Dorothy K, Nichols Colin G

Abstract excerpt

Background Cardiomegaly caused by left ventricular hypertrophy is a risk factor for development of congestive heart failure, classically associated with decreased systolic and/or diastolic ventricular function. Less attention has been given to the phenotype of left ventricular hypertrophy with enhanced ventricular function and increased cardiac output, which is potentially associated with high-output heart...

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Source

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Identifiers

PMID: 36515236
DOI: 10.1161/JAHA.122.027363
PMCID: PMC9798820

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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