Article
Blood-based microRNA signatures differentiate various forms of cardiac hypertrophy.
International journal of cardiology - 1 Oct 2015
Derda Anselm A, Thum Sabrina, Lorenzen Johan M, Bavendiek Udo, Heineke Joerg, Keyser Britta, Stuhrmann Manfred, Givens Raymond C, Kennel Peter J, Schulze P Christian, Widder Julian D, Bauersachs Johann, Thum Thomas
Abstract excerpt
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is caused by mutations in different structural genes and induces pathological hypertrophy with sudden cardiac death as a possible consequence. HCM can be separated into hypertrophic non-obstructive and obstructive cardiomyopathy (HNCM/HOCM) with different clinical treatment approaches. We here distinguished between HNCM, HOCM, cardiac amyloidosis and aortic stenosis...
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