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Article

Multiple myeloma, a quintessential malignant disease of aging: a geroscience perspective on pathogenesis and treatment

12 Dec 2022

Abstract excerpt

Multiple myeloma (MM) is an incurable plasma cell malignancy, which is predominantly a disease of older adults (the median age at diagnosis is 70 years). The slow progression from asymptomatic stages and the late-onset of MM suggest fundamental differences compared to many other hematopoietic system-related malignancies. The concept discussed in this review is that age-related changes at the level of terminally...

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PMID: 36508077
DOI: 10.1007/s11357-022-00698-x

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