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Article

Impact of fluoroquinolones and aminoglycosides on P. aeruginosa virulence factor production and cytotoxicity.

The Biochemical journal - 22 Dec 2022

Foulkes Daniel M, McLean Keri, Sloniecka Marta, Rustidge Sophie, Byrne Dominic P, Haneef Atikah S, Winstanley Craig, Berry Neil, Fernig David G, Kaye Stephen B

Abstract excerpt

The opportunistic pathogen Pseudomonas aeruginosa is one of leading causes of disability and mortality worldwide and the world health organisation has listed it with the highest priority for the need of new antimicrobial therapies. P. aeruginosa strains responsible for the poorest clinical outcomes express either ExoS or ExoU, which are injected into target host cells via the type III secretion system (T3SS)....

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PMID: 36504127
DOI: 10.1042/BCJ20220527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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