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Article

Comprehensive Transcriptomic Analysis of VISTA in Acute Myeloid Leukemia: Insights into Its Prognostic Value.

International journal of molecular sciences - 28 Nov 2022

Pagliuca Simona, Gurnari Carmelo, Zhang Keman, Kewan Tariq, Bahaj Waled, Mori Minako, Nautiyal Ishani, Rubio Marie Thérèse, Ferraro Francesca, Maciejewski Jaroslaw P, Wang Li, Visconte Valeria

Abstract excerpt

The V-domain Ig suppressor of T-cell activation (VISTA) has been recognized as a critical negative regulator of antitumor immune response and is gaining growing interest as a potential pharmacological target in immunotherapy. This molecule is highly expressed in hematopoietic stem cells and myeloid compartment, and it has been found upmodulated in acute myeloid leukemia (AML). However, VISTA-associated immune...

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PMID: 36499220
DOI: 10.3390/ijms232314885
PMCID: PMC9735915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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