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Article

Analysis of mutational history of multidrug-resistant genotypes with a mutagenetic tree model.

Journal of medical virology - 1 Jan 2023

Pirkl Martin, Büch Joachim, Devaux Carole, Böhm Michael, Sönnerborg Anders, Incardona Francesca, Abecasis Ana, Vandamme Anne-Mieke, Zazzi Maurizio, Kaiser Rolf, Lengauer Thomas, The EuResist Network Study Group

Abstract excerpt

Human immunodeficiency virus (HIV) can develop resistance to all antiretroviral drugs. Multidrug resistance, however, is a rare event in modern HIV treatment, but can be life-threatening, particular in patients with very long therapy histories and in areas with limited access to novel drugs. To understand the evolution of multidrug resistance, we analyzed the EuResist database to uncover the accumulation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36484375
DOI: 10.1002/jmv.28389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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