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Article

Distinct clinical pattern of colorectal cancer patients with POLE mutations: A retrospective study on real-world data

21 Nov 2022

Abstract excerpt

Objective: Studies have demonstrated an association between somatic POLE exonuclease domain mutations (EDMs) and the prognosis of colorectal cancer (CRC). However, the prognostic value of POLE non-EDMs remains unclear. This retrospective study aimed to explore the possible relationships between POLE mutation subtypes and CRC prognosis. Methods: The 272 CRC patients from the First Affiliated Hospital of Zhengzhou...

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Identifiers

PMID: 36479248
DOI: 10.3389/fgene.2022.963964

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