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Article

SMAD2 rs4940086 heterozygosity increases the risk of cervical cancer development among the women in Bangladesh.

Molecular biology reports - 1 Jul 2020

Haque Parsa Sanjana, Apu Mohd Nazmul Hasan, Nahid Noor Ahmed, Islam Farhana, Islam Md Reazul, Hasnat Abul, Islam Md Saiful

Abstract excerpt

SMAD2 is a critical signal transducer molecule in the TGFβ- SMAD pathway which is also known for its tumor suppressor role. Genetic variations in SMAD2 render cells insensitive to its anti-proliferative signals leading to tumor formation. In this study, we demonstrate the impact of single nucleotide polymorphisms (SNPs) of SMAD2 (rs4940086 and rs8085335) on cervical cancer risk development in Bangladeshi...

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Identifiers

PMID: 32507921
DOI: 10.1007/s11033-020-05572-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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