Article
Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder.
Molecular psychiatry - 1 Aug 2021
O'Connell Kevin S, Shadrin Alexey, Bahrami Shahram, Smeland Olav B, Bettella Francesco, Frei Oleksandr, Krull Florian, Askeland Ragna B, Walters G Bragi, Davíðsdóttir Katrín, Haraldsdóttir Gyða S, Guðmundsson Ólafur Ó, Stefánsson Hreinn, Fan Chun C, Steen Nils Eiel, Reichborn-Kjennerud Ted, Dale Anders M, Stefánsson Kári, Djurovic Srdjan, Andreassen Ole A
Abstract excerpt
Differential diagnosis between childhood onset attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) remains a challenge, mainly due to overlapping symptoms and high rates of comorbidity. Despite this, genetic correlation reported for these disorders is low and non-significant. Here we aimed to better characterize the genetic architecture of these disorders utilizing recent large genome-wide...
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