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Article

Comparison of PIK3CA Mutation Prevalence in Breast Cancer Across Predicted Ancestry Populations.

JCO precision oncology - 1 Nov 2022

Chen Jessica W, Murugesan Karthikeyan, Newberg Justin Y, Sokol Ethan S, Savage Heidi M, Stout Thomas J, Maund Sophia L, Hutchinson Katherine E

Abstract excerpt

PURPOSE: Understanding the differences in biomarker prevalence that may exist among diverse populations is invaluable to accurately forecast biomarker-driven clinical trial enrollment metrics and to advance inclusive research and health equity. This study evaluated the frequency and types of PIK3CA mutations (PIK3CAmut) detected in predicted genetic ancestry subgroups across breast cancer (BC) subtypes. METHODS:...

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Identifiers

PMID: 36446041
DOI: 10.1200/PO.22.00341
PMCID: PMC9812634

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