Article
Association of LTA and SOD Gene Polymorphisms with Cerebral White Matter Hyperintensities in Migraine Patients.
International journal of molecular sciences - 9 Nov 2022
Ferroni Patrizia, Palmirotta Raffaele, Egeo Gabriella, Aurilia Cinzia, Valente Maria Giovanna, Spila Antonella, Pierallini Alberto, Barbanti Piero, Guadagni Fiorella
Abstract excerpt
White matter hyperintensities (WMHs) in migraine could be related to inflammatory and antioxidant events. The aim of this study is to verify whether migraine patients with WMHs carry a genetic pro-inflammatory/pro-oxidative status. To test this hypothesis, we analyzed lymphotoxin alpha (LTA; rs2071590T and rs2844482G) and superoxide dismutase 1 (SOD1; rs2234694C) and 2 (SOD2; rs4880T) gene polymorphisms (SNPs) in...
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