Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanistic and Clinical Evidence Supports a Key Role for Cell Division Cycle Associated 5 (CDCA5) as an Independent Predictor of Outcome in Invasive Breast Cancer

17 Nov 2022

Abstract excerpt

Background: Cell Division Cycle Associated 5 (CDCA5) plays a role in the phosphoinositide 3-kinase (PI3K)/AKT/mTOR signalling pathway involving cell division, cancer cell migration and apoptosis. This study aims to assess the prognostic and biological value of CDCA5 in breast cancer (BC). Methods: The biological and prognostic value of CDCA5 were evaluated at mRNA (n = 5109) and protein levels (n = 614) utilizing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36428736
DOI: 10.3390/cancers14225643

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanistic and Clinical Evidence Supports a Key Role for Cell Division Cycle Associated 5 (CDCA5) as an Independent Predictor of Outcome in Invasive Breast CancerPMID 36428736Read ↗

Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathwaySemantic proximity Read ↗

DLGAP5 Regulates the Proliferation, Migration, Invasion, and Cell Cycle of Breast Cancer Cells via the JAK2/STAT3 Signaling AxisSemantic proximity Read ↗

Prognostic and Therapeutic Implications of Cell Division Cycle 20 Homolog in Breast CancerSemantic proximity Read ↗

KDM5 family as therapeutic targets in breast cancer: Pathogenesis and therapeutic opportunities and challengesSemantic proximity Read ↗

CDCA8, a mitosis-related gene, as a prospective pan-cancer biomarker: implications for survival prognosis and oncogenic immunologySemantic proximity Read ↗

Higher expression of cell division cycle-associated protein 5 predicts poorer survival outcomes in hepatocellular carcinoma.Semantic proximity Read ↗

Cell Division Cycle-Associated Protein 8 in Pan-Cancer: A Comprehensive Prognostic and Immune Infiltration InvestigationSemantic proximity Read ↗

CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathwaySemantic proximity Read ↗

Identification of novel biomarkers in breast cancer via integrated bioinformatics analysis and experimental validationSemantic proximity Read ↗

HDHD5 promotes triple-negative breast cancer growth and drives EMT-associated phenotypes via regulating S100A4.Semantic proximity Read ↗

Cell division cycle associated 8: A novel diagnostic and prognostic biomarker for hepatocellular carcinomaSemantic proximity Read ↗

Upregulation of CDCA5 promotes gastric cancer malignant progression via influencing cyclin E1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.