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Article

Variants in the inflammatory IL6 and MPO genes modulate stroke susceptibility through main effects and gene-gene interactions.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Aug 2011

Manso Helena, Krug Tiago, Sobral João, Albergaria Isabel, Gaspar Gisela, Ferro José M, Oliveira Sofia A, Vicente Astrid M

Abstract excerpt

There is substantial evidence that inflammation within the central nervous system contributes to stroke risk and recovery. Inflammatory conditions increase stroke risk, and the inflammatory response is of major importance in recovery and healing processes after stroke. We investigated the role of inflammatory genes IL1B, IL6, MPO, and TNF in stroke susceptibility and recovery in a population sample of 672...

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Source

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Identifiers

PMID: 21407237
DOI: 10.1038/jcbfm.2011.27
PMCID: PMC3170942

Genes

MPO
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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