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Article

Genetic evidence for causal relationships between age at natural menopause and the risk of ageing-associated adverse health outcomes.

International journal of epidemiology - 6 Jun 2023

Lankester Joanna, Li Jin, Salfati Elias Levy Itshak, Stefanick Marcia L, Chan Kei Hang Katie, Liu Simin, Crandall Carolyn J, Clarke Shoa L, Assimes Themistocles L

Abstract excerpt

BACKGROUND: A later age at natural menopause (ANM) has been linked to several ageing-associated traits including an increased risk of breast and endometrial cancer and a decreased risk of lung cancer, osteoporosis and Alzheimer disease. However, ANM is also related to several proxies for overall health that may confound these associations. METHODS: We investigated the causal association of ANM with these clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36409989
DOI: 10.1093/ije/dyac215
PMCID: PMC10244052

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