Article
Two-Period Study Results from a Large Italian Hospital Laboratory Attesting SARS-CoV-2 Variant PCR Assay Evolution.
Microbiology spectrum - 21 Dec 2022
Liotti Flora Marzia, De Maio Flavio, Ippoliti Chiara, Santarelli Giulia, Monzo Francesca Romana, Sali Michela, Santangelo Rosaria, Ceccherini-Silberstein Francesca, Sanguinetti Maurizio, Posteraro Brunella
Abstract excerpt
In keeping with the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the COVID-19 causative agent, PCR assays have been developed to rapidly detect SARS-CoV-2 variants, which have emerged since the first (Alpha) variant was identified. Based on specific assortment of SARS-CoV-2 spike-protein mutations (ΔH69/V70, E484K, N501Y, W152C, L452R, K417N, and K417T) among the major variants known...
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