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Article

Wide Real-Life Data Support Reduced Sensitivity of Antigen Tests for Omicron SARS-CoV-2 Infections.

Viruses - 23 Apr 2024

Piubelli Chiara, Treggiari Davide, Lavezzari Denise, Deiana Michela, Dishnica Klevia, Tosato Emma Maria Sole, Mazzi Cristina, Cattaneo Paolo, Mori Antonio, Pomari Elena, Nicolini Lavinia, Leonardi Martina, Perandin Francesca, Formenti Fabio, Giorgetti Alejandro, Conti Antonio, Capobianchi Maria Rosaria, Gobbi Federico Giovanni, Castilletti Concetta

Abstract excerpt

With the continuous spread of new SARS-CoV-2 variants of concern (VOCs), the monitoring of diagnostic test performances is mandatory. We evaluated the changes in antigen diagnostic tests' (ADTs) accuracy along the Delta to Omicron VOCs transition, exploring the N protein mutations possibly affecting ADT sensitivity and assessing the best sampling site for the diagnosis of Omicron infections. In total, 5175...

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Identifiers

PMID: 38793539
DOI: 10.3390/v16050657
PMCID: PMC11125898

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